T cells modulate IL-4 expression by eosinophil recruitment within decellularized scaffolds to repair nerve defects
Abstract
Decellularized nerve, or acellular nerve allografts (ANAs), are an increasingly used alternative to nerve autografts to repair nerve gaps to facilitate regeneration. The adaptive immune system, specifically T cells, plays a role in promoting regeneration upon these ANA scaffolds. However, how T cells promote regeneration across ANAs is not clear. Here, we show that T cells accumulate within ANAs repairing nerve gaps resulting in regulation of...
Paper Details
Title
T cells modulate IL-4 expression by eosinophil recruitment within decellularized scaffolds to repair nerve defects
Published Date
Aug 1, 2020
Journal
Volume
112
Pages
149 - 163
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