Acta Biomaterialia
Papers 6662
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#1Maëla Choimet (University of Toulouse)
#2A. Tourrette (University of Toulouse)H-Index: 9
Last. Christophe Drouet (University of Toulouse)H-Index: 28
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Abstract Most treatments of skin pathologies involve local administration of active agents. One issue can however be the partial transcutaneous diffusion of the drug to blood circulation, leading to undesirable effects. In this work, the original use of submicron mineral particles based on bio-inspired calcium phosphate apatite was explored for the first time as drug carriers for favoring topical delivery. The permeation of a model drug across synthetic and biological membranes was investigated ...
#1Nurit Adiram-Filiba (BIU: Bar-Ilan University)H-Index: 2
#2Yasmin Geiger (BIU: Bar-Ilan University)H-Index: 3
Last. Gil Goobes (BIU: Bar-Ilan University)H-Index: 14
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Abstract Many life forms generate intricate submicron biosilica structures with various important biological functions. The formation of such structures, from the silicic acid in the waters and in the soil, is thought to be regulated by unique proteins with high repeats of specific amino acids and unusual sidechain modifications. Some silicifying proteins are characterized by high prevalence of basic amino acids in their primary structures. Lysine-rich domains are found, for instance, in diatom ...
#1Duc Dung NguyenH-Index: 2
#2Li-Jyuan LuoH-Index: 1
Last. Jui-Yang LaiH-Index: 27
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#1Dong Hwa KimH-Index: 11
#2Julianne HuegelH-Index: 8
Last. Andrew F. KuntzH-Index: 10
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#1Xifeng LiuH-Index: 12
#2Matthew N. GeorgeH-Index: 2
Last. Lichun LuH-Index: 30
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#1Ya Su (Changchun University)H-Index: 1
Last. Min Zheng (Changchun University)H-Index: 22
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Abstract Recently, organic dyes with aggregation-induced emission (AIE) have attracted much attention in bioimaging and diagnostics. Relatively, the application of traditional dyes has diminished because of aggregation-caused quenching (ACQ). In this work, we compare the imaging ability of nanoparticle formulations of these two kinds of dyes. Boron dipyrromethene (BODIPY) was chosen as a representative of the ACQ dyes, and an aggregation-induced emission (AIE) dye BPMT was used for comparison. B...
#1Deng Pan (WashU: Washington University in St. Louis)H-Index: 1
#2Daniel A. Hunter (WashU: Washington University in St. Louis)H-Index: 50
Last. Matthew D. Wood (WashU: Washington University in St. Louis)H-Index: 19
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Abstract Decellularized nerve, or acellular nerve allografts (ANAs), are an increasingly used alternative to nerve autografts to repair nerve gaps to facilitate regeneration. The adaptive immune system, specifically T cells, plays a role in promoting regeneration upon these ANA scaffolds. However, how T cells promote regeneration across ANAs is not clear. Here, we show that T cells accumulate within ANAs repairing nerve gaps resulting in regulation of cytokine expression within the ANA environme...
Top fields of study
Biomedical engineering
Composite material
Organic chemistry
Materials science
Tissue engineering