Collagen-binding IL-12 inflames ‘cold’ tumours
Abstract
The intravenous administration of a formulation of interleukin-12 that binds to collagen in established ‘immunologically cold’ murine tumours enhances interferon-γ production by T cells and causes tumour remission, especially when in combination with immune checkpoint blockade...
Paper Details
Title
Collagen-binding IL-12 inflames ‘cold’ tumours
Published Date
May 14, 2020
Volume
4
Issue
5
Pages
483 - 484
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History