Localized delivery of active targeting micelles from nanofibers patch for effective breast cancer therapy

Nanofibers based transdermal drug delivery is a promising platform, and it effectively delivers the drug to tumor sites. The objective of the study was to fabricate stimuli-responsive polymeric nanofibers encapsulated with an active targeting micellar system for in situ drug delivery. Stimuli-responsive core–shell nanofibers release the drug at target sites with minimum side effects to the other organs, decrease the drug administration...