Potential role for rTMS in treating Primary Orthostatic Tremor

Primary orthostatic tremor (POT) is a rare progressive disabling tremor disorder characterized by symptoms of unsteadiness when standing, which improves upon walking or sitting and a distinct high frequency (13–18Hz) tremor discharge recorded from the leg muscles [1]. Treatment opportunities for POT are poor as the pharmacological therapies, including the propranolol, clonazepam and gabapentin and surgical intervention through thalamic deep...