Response to: ‘Is non-industrial society undergoing an energy balance transition predisposed to accumulate abdominal adipose tissue and susceptible to knee osteoarthritis?’ by Yuet al

Many thanks to Yu and colleagues1 for their interest in our recent paper on knee osteoarthritis (OA) susceptibility among the Tarahumara, an indigenous population of subsistence farmers in Mexico undergoing rapid lifestyle changes that promote positive energy balance.2 We welcome their constructive comments and are happy to respond. As Yu et al point out, a key prediction of the model we proposed for knee OA risk among non-industrial societies...