ST2 as checkpoint target for colorectal cancer immunotherapy
Abstract
Immune checkpoint blockade immunotherapy delivers promising clinical results in colorectal cancer (CRC). However, only a fraction of cancer patients develop durable responses. The tumor microenvironment (TME) negatively impacts tumor immunity and subsequently clinical outcomes. Therefore, there is a need to identify other checkpoint targets associated with the TME. Early-onset factors secreted by stromal cells as well as tumor cells often help...
Paper Details
Title
ST2 as checkpoint target for colorectal cancer immunotherapy
Published Date
May 7, 2020
Journal
Volume
5
Issue
9
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