Original paper

Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation

eLife6.40
Volume: 9
Published: Apr 24, 2020
Abstract
A highly aggressive subset of pancreatic ductal adenocarcinomas undergo trans-differentiation into the squamous lineage during disease progression. Here, we investigated whether squamous trans-differentiation of human and mouse pancreatic cancer cells can influence the phenotype of non-neoplastic cells in the tumor microenvironment. Conditioned media experiments revealed that squamous pancreatic cancer cells secrete factors that recruit...
Paper Details
Title
Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation
Published Date
Apr 24, 2020
Journal
Volume
9
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.