Review paper
Microtubule Retrograde Motors and Their Role in Retroviral Transport
Abstract
Following entry into the host cell, retroviruses generate a dsDNA copy of their genomes via reverse transcription, and this viral DNA is subsequently integrated into the chromosomal DNA of the host cell. Before integration can occur, however, retroviral DNA must be transported to the nucleus as part of a ‘preintegration complex’ (PIC). Transporting the PIC through the crowded environment of the cytoplasm is challenging, and retroviruses have...
Paper Details
Title
Microtubule Retrograde Motors and Their Role in Retroviral Transport
Published Date
Apr 24, 2020
Journal
Volume
12
Issue
4
Pages
483 - 483
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