Striatal Dopamine and Reward Prediction Error Signaling in Unmedicated Schizophrenia Patients
Abstract
Increased striatal dopamine synthesis capacity has consistently been reported in patients with schizophrenia. However, the mechanism translating this into behavior and symptoms remains unclear. It has been proposed that heightened striatal dopamine may blunt dopaminergic reward prediction error signaling during reinforcement learning. In this study, we investigated striatal dopamine synthesis capacity, reward prediction errors, and their...
Paper Details
Title
Striatal Dopamine and Reward Prediction Error Signaling in Unmedicated Schizophrenia Patients
Published Date
Apr 22, 2020
Journal
Volume
46
Issue
6
Pages
1535 - 1546
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