Relationship of sputum mast cells with clinical and inflammatory characteristics of asthma

Background Mast cells (MCs) are innate immune cells that regulate atopic and non‐atopic inflammation in the airways. MCs play a critical role in the pathogenesis of asthma, yet their relationship to airway and systemic inflammation and clinical characteristics of asthma is poorly understood. Objective To quantify MCs in induced sputum samples and understand their relationship to airway and circulatory immune cells, and clinical variables in...