Loss of N-Glycanase 1 Alters Transcriptional and Translational Regulation in K562 Cell Lines
Abstract
N-Glycanase 1 (NGLY1) deficiency is an ultra-rare, complex and devastating neuromuscular disease. Patients display multi-organ symptoms including developmental delays, movement disorders, seizures, constipation and lack of tear production. NGLY1 is a deglycosylating protein involved in the degradation of misfolded proteins retrotranslocated from the endoplasmic reticulum (ER). NGLY1-deficient cells have been reported to exhibit decreased...
Paper Details
Title
Loss of N-Glycanase 1 Alters Transcriptional and Translational Regulation in K562 Cell Lines
Published Date
May 1, 2020
Journal
Volume
10
Issue
5
Pages
1585 - 1597
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History