Review paper
Germline Elongator mutations in Sonic Hedgehog medulloblastoma
Abstract
Cancer genomics has revealed many genes and core molecular processes that contribute to human malignancies, but the genetic and molecular bases of many rare cancers remains unclear. Genetic predisposition accounts for 5 to 10% of cancer diagnoses in children1,2, and genetic events that cooperate with known somatic driver events are poorly understood. Pathogenic germline variants in established cancer predisposition genes have been recently...
Paper Details
Title
Germline Elongator mutations in Sonic Hedgehog medulloblastoma
Published Date
Apr 1, 2020
Journal
Volume
580
Issue
7803
Pages
396 - 401
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