Review paper
Epigenetic regulation of epithelial-mesenchymal transition: focusing on hypoxia and TGF-β signaling
Abstract
Epithelial-mesenchymal transition (EMT) is an important process triggered during cancer metastasis. Regulation of EMT is mostly initiated by outside signalling, including TGF-β, growth factors, Notch ligand, Wnt, and hypoxia. Many signalling pathways have been delineated to explain the molecular mechanisms of EMT. In this review, we will focus on the epigenetic regulation of two critical EMT signalling pathways: hypoxia and TGF-β. For hypoxia,...
Paper Details
Title
Epigenetic regulation of epithelial-mesenchymal transition: focusing on hypoxia and TGF-β signaling
Published Date
Mar 2, 2020
Volume
27
Issue
1
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