Review paper
PDE4 subtypes in cancer
Abstract
Cyclic nucleotide phosphodiesterases (PDE) break down cyclic nucleotides such as cAMP and cGMP, reducing the signaling of these important intracellular second messengers. Several unique families of phosphodiesterases exist, and certain families are clinically important modulators of vasodilation. In the current work, we have summarized the body of literature that describes an emerging role for the PDE4 subfamily of phosphodiesterases in...
Paper Details
Title
PDE4 subtypes in cancer
Published Date
Mar 20, 2020
Journal
Volume
39
Issue
19
Pages
3791 - 3802
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