Original paper
Unconventional Secondary Structure Mimics: Ladder‐Rungs
Abstract
Secondary structures tend to be recognizable because they have repeating structural motifs, but mimicry of these does not have to follow such well‐defined patterns. Bioinformatics studies to match side‐chain orientations of a novel hydantoin triazole chemotype ( 1 ) to protein‐protein interfaces revealed it tends to align well across parallel and antiparallel sheets, like rungs on a ladder. One set of these overlays was observed for the...
Paper Details
Title
Unconventional Secondary Structure Mimics: Ladder‐Rungs
Published Date
Apr 20, 2020
Journal
Volume
59
Issue
24
Pages
9398 - 9402
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Notes
History