Original paper

Clarifying the Risk of Lung Disease in SZ Alpha-1 Antitrypsin Deficiency

Volume: 202, Issue: 1, Pages: 73 - 82
Published: Jul 1, 2020
Abstract
Rationale: The ZZ genotype of alpha-1 antitrypsin deficiency (AATD) is associated with chronic obstructive pulmonary disease (COPD), even among never-smokers. The SZ genotype is also considered severe; yet, its effect on lung health remains unclear.Objectives: To determine the effect of SZ-AATD on spirometry compared with a normal-risk population and to determine the effect of smoking cessation in this genotype.Methods: We prospectively enrolled...
Paper Details
Title
Clarifying the Risk of Lung Disease in SZ Alpha-1 Antitrypsin Deficiency
Published Date
Jul 1, 2020
Volume
202
Issue
1
Pages
73 - 82
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