RATIONALE: Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease (COVID-19), a predominantly respiratory illness. The first step in SARS-CoV-2 infection is binding of the virus to angiotensin converting enzyme 2 (ACE2) on the airway epithelium. OBJECTIVES: The objective was to gain insight into the expression of ACE2 in the human airway epithelium. METHODS: Airway epithelium sampled by fiberoptic bronchoscopy of trachea, large airway epi-theli...
Background and Rationale: ICU clinicians regularly care for patients who lack capacity, an applicable advance directive, and an available surrogate decision-maker. Although there is no consensus on...
Last. Steven M. Rowe(UAB: University of Alabama at Birmingham)H-Index: 44
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Cystic fibrosis (CF) remains the most common life-shortening hereditary disease in Caucasian populations with high morbidity and mortality related to chronic airway mucus obstruction, inflammation,...