Dead Cells Induce Innate Anergy via Mertk after Acute Viral Infection
Abstract
Infections can result in a temporarily restricted unresponsiveness of the innate immune response, thereby limiting pathogen control. Mechanisms of such unresponsiveness are well studied in lipopolysaccharide tolerance; however, whether mechanisms of tolerance limit innate immunity during virus infection remains unknown. Here, we find that infection with the highly cytopathic vesicular stomatitis virus (VSV) leads to innate anergy for several...
Paper Details
Title
Dead Cells Induce Innate Anergy via Mertk after Acute Viral Infection
Published Date
Mar 1, 2020
Journal
Volume
30
Issue
11
Pages
3671 - 3681.e5
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