Original paper
Gαq splice variants mediate phototransduction, rhodopsin synthesis, and retinal integrity in Drosophila
Abstract
Heterotrimeric G proteins mediate a variety of signaling processes by coupling G protein–coupled receptors to intracellular effector molecules. In Drosophila, the Gαq gene encodes several Gαq splice variants, with the Gαq1 isoform protein playing a major role in fly phototransduction. However, Gαq1 null mutant flies still exhibit a residual light response, indicating that other Gαq splice variants or additional Gq α subunits are involved in...
Paper Details
Title
Gαq splice variants mediate phototransduction, rhodopsin synthesis, and retinal integrity in Drosophila
Published Date
Apr 1, 2020
Volume
295
Issue
17
Pages
5554 - 5563
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