Original paper

Extraction of Thick Filaments in Individual Sarcomeres Affects Force Production by Single Myofibrils

Volume: 118, Issue: 8, Pages: 1921 - 1929
Published: Apr 1, 2020
Abstract
It has been accepted that the force produced by a skeletal muscle myofibril depends on its cross-sectional area but not on the number of active sarcomeres because they are arranged in series. However, a previous study performed by our group showed that blocking actomyosin interactions within an activated myofibril and depleting the thick filaments in one sarcomere unexpectedly reduced force production. In this study, we examined in detail how...
Paper Details
Title
Extraction of Thick Filaments in Individual Sarcomeres Affects Force Production by Single Myofibrils
Published Date
Apr 1, 2020
Volume
118
Issue
8
Pages
1921 - 1929
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