Review paper
CNS-Derived Blood Exosomes as a Promising Source of Biomarkers: Opportunities and Challenges
Abstract
Eukaryotic cells release different types of extracellular vesicles (EVs) including exosomes, ectosomes, and microvesicles. Exosomes are nanovesicles, 30-200 nm in diameter, that carry cell- and cell-state-specific cargo of proteins, lipids, and nucleic acids, including mRNA and miRNA. Recent studies have shown that central nervous system (CNS)-derived exosomes may carry amyloidogenic proteins and facilitate their cell-to-cell transfer, thus...
Paper Details
Title
CNS-Derived Blood Exosomes as a Promising Source of Biomarkers: Opportunities and Challenges
Published Date
Mar 19, 2020
Volume
13
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