Diagnostic performance of D-dimer in predicting venous thromboembolism and acute aortic dissection

D-dimer is elevated in a variety of conditions. The purpose of this study was to assess the positive predictive value of D-dimer to rule in patients with confirmed pulmonary embolism, deep vein thrombosis, acute aortic dissection or thrombosis of the upper extremity in comparison to patients with elevated D-dimer for other reasons.We studied 1334 patients presenting to the emergency department with pulmonary embolism (n=193), deep vein...