Risk Factors for Acetaminophen-induced Liver Injury: A Single-center Study from Japan

Purpose Acetaminophen has been increasingly used for the treatment of cancer-related pain in Japan since the revision of the package insert on January 21, 2011. However, high-dose acetaminophen may cause liver injury. The objectives of this study were to investigate the prevalence of liver injury in patients receiving acetaminophen and to identify the risk factors. Methods The subjects were patients who were treated with acetaminophen ≥1500 mg/d...