Review paper
The IGF/Insulin-IGFBP Axis in Corneal Development, Wound Healing, and Disease
Abstract
The insulin-like growth factor (IGF) family plays key roles in growth and development. In the cornea, IGF family members have been implicated in proliferation, differentiation, and migration, critical events that maintain a smooth refracting surface that is essential for vision. The IGF family is composed of multiple ligands, receptors, and ligand binding proteins. Expression of IGF type 1 receptor (IGF-1R), IGF type 2 receptor (IGF-2R), and...
Paper Details
Title
The IGF/Insulin-IGFBP Axis in Corneal Development, Wound Healing, and Disease
Published Date
Mar 3, 2020
Journal
Volume
11
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