Review paper

A Bump in the Road: How the Hostile AML Microenvironment Affects CAR T Cell Therapy

Volume: 10
Published: Feb 28, 2020
Abstract
Chimeric antigen receptor (CAR) T cells targeting CD19 have been successful treating patients with relapsed/refractory B cell acute lymphoblastic leukemia (ALL) and B cell lymphomas. However, relapse after CAR T cell therapy is still a challenge. In addition, preclinical and early clinical studies targeting acute myeloid leukemia (AML) have not been as successful. This can be attributed in part to the presence of an AML microenvironment that has...
Paper Details
Title
A Bump in the Road: How the Hostile AML Microenvironment Affects CAR T Cell Therapy
Published Date
Feb 28, 2020
Volume
10
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.