Original paper
Dysregulated metabolic pathways in age-related macular degeneration
Abstract
Age-related macular degeneration is a major cause of vision impairment in the Western world among people of 55 years and older. Recently we have shown that autophagy is dysfunctional in the retinal pigment epithelium (RPE) of the AMD donor eyes (AMD RPE). We also showed increased reactive oxygen (ROS) production, increased cytoplasmic glycogen accumulation, mitochondrial dysfunction and disintegration, and enlarged and annular LAMP-1-positive...
Paper Details
Title
Dysregulated metabolic pathways in age-related macular degeneration
Published Date
Feb 12, 2020
Journal
Volume
10
Issue
1
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Notes
History