Meta-analysis and systematic review of ADGRL3 (LPHN3) polymorphisms in ADHD susceptibility

Estela M. Bruxel; Carlos Renato Moreira-Maia; Glaucia Chiyoko Akutagava-Martins; Thomas P. Quinn; Marieke Klein; Barbara Franke; M. Ribasés; Paula Rovira; Cristina Sánchez-Mora; Djenifer B. Kappel; Mara H. Hutz

doi:https://doi.org/10.1038/s41380-020-0673-0

doi.org/10.1038/s41380-020-0673-0

Meta-analysis and systematic review of ADGRL3 (LPHN3) polymorphisms in ADHD susceptibility

Estela M. Bruxel

8

,

Carlos Renato Moreira-Maia

9

,

..., Mara H. Hutz

43

Molecular Psychiatry11.00

Volume: 26, Issue: 6, Pages: 2277 - 2285

Published: Feb 12, 2020

Abstract

The gene encoding adhesion G protein-coupled receptor L3 (ADGRL3, also referred to as latrophilin 3 or LPHN3) has been associated with ADHD susceptibility in independent ADHD samples. We conducted a systematic review and a comprehensive meta-analysis to summarize the associations between the most studied ADGRL3 polymorphisms (rs6551665, rs1947274, rs1947275, and rs2345039) and both childhood and adulthood ADHD. Eight association studies (seven...

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Paper Details

Title

Meta-analysis and systematic review of ADGRL3 (LPHN3) polymorphisms in ADHD susceptibility

DOI

doi.org/10.1038/s41380-020-0673-0

Published Date

Feb 12, 2020

Journal

Molecular Psychiatry

Volume

26

Issue

6

Pages

2277 - 2285

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