Oxytocin modulates intrinsic neural activity in patients with chronic low back pain

Background Modulation of pain perception by oxytocin (OXT) has attracted increased scientific and clinical interest. Neural mechanisms underlying these effects are poorly understood. In this study, we aimed to investigate the effects of intranasally applied OXT on intrinsic neural activity in patients with chronic low back pain (cLBP). Methods Twenty‐four male patients with cLBP and 23 healthy males were examined using resting‐state functional...