Discovering the genes mediating the interactions between chronic respiratory diseases in the human interactome
Abstract
The molecular and clinical features of a complex disease can be influenced by other diseases affecting the same individual. Understanding disease-disease interactions is therefore crucial for revealing shared molecular mechanisms among diseases and designing effective treatments. Here we introduce Flow Centrality (FC), a network-based approach to identify the genes mediating the interaction between two diseases in a protein-protein interaction...
Paper Details
Title
Discovering the genes mediating the interactions between chronic respiratory diseases in the human interactome
Published Date
Feb 10, 2020
Journal
Volume
11
Issue
1
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