Original paper
Cullin 3 targets the tumor suppressor gene ARMC5 for ubiquitination and degradation
Abstract
ARMC5 (Armadillo repeat containing 5 gene) was identified as a new tumor suppressor gene responsible for hereditary adrenocortical tumors and meningiomas. ARMC5 is ubiquitously expressed and encodes a protein which contains a N-terminal Armadillo repeat domain and a C-terminal BTB (Bric-a-Brac, Tramtrack and Broad-complex) domain, both docking platforms for numerous proteins. At present, expression regulation and mechanisms of action of ARMC5...
Paper Details
Title
Cullin 3 targets the tumor suppressor gene ARMC5 for ubiquitination and degradation
Published Date
Apr 1, 2020
Journal
Volume
27
Issue
4
Pages
221 - 230
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Notes
History