STAT1 transcriptionally regulates the expression of S1PR1 by binding its promoter region

Gene3.50
Volume: 736, Pages: 144417 - 144417
Published: Apr 1, 2020
Abstract
Sphingosine 1-phosphate receptor 1 (S1PR1) plays a pivotal role in mediating trafficking and migration of immune cells. Previous reports also identify S1PR1 as an important susceptibility gene of asthma and other autoimmune disorders. However, little has been known about the regulatory mechanism of S1PR1 expression. Thus we systematically investigated the transcriptional regulation of S1PR1 in this study. Promoter activity of S1PR1 gene was...
Paper Details
Title
STAT1 transcriptionally regulates the expression of S1PR1 by binding its promoter region
Published Date
Apr 1, 2020
Journal
Volume
736
Pages
144417 - 144417
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