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Published in Gene2.64
Sheeraz Un Nazir2
Estimated H-index: 2
(ICMR: Indian Council of Medical Research),
Ramesh Kumar31
Estimated H-index: 31
(Bundelkhand University)
+ -3 AuthorsShowket Hussain18
Estimated H-index: 18
(ICMR: Indian Council of Medical Research)
Published in Gene2.64
Hai-bo Zhao (ZJU: Zhejiang University), Hui-min Jia4
Estimated H-index: 4
(ZJU: Zhejiang University)
+ -3 AuthorsZhongshan Gao18
Estimated H-index: 18
(ZJU: Zhejiang University)
Abstract The MADS-box gene family encodes transcription factors and plays an important role in plant growth and the development of flower and fruit. A perennial dioecious plant, the red bayberry genome has been published recently, providing the opportunity to analyze the MADS-box gene family and its role in fruit development and ripening. Here, we identified 54 MADS-box genes in the red bayberry genome, and classified them into two types based on phylogenetic analysis. Thirteen Type I MADS-box g...
Published in Gene2.64
Tuo Shao (HMU: Harbin Medical University), Yuhang Hu (HMU: Harbin Medical University)+ -3 AuthorsJiaao Gu (HMU: Harbin Medical University)
Abstract Intervertebral disc degeneration (IDD) is a major cause of lower back pain, but the specific molecular mechanisms governing its development are poorly characterized. This study sought to assess to what extent HOTAIR, a long non-coding (Lnc) RNA is expressed in IDD and regulates the apoptotic death of nucleus pulposus (NP) cells. We therefore used real-time qPCR to measure HOTAIR and microRNA(miR)-34a-5p in degenerative NP cells, and then validated their functional relevance via overexpr...
Published in Gene2.64
Zhijin Li (Xi'an Jiaotong University), Hua Tan9
Estimated H-index: 9
(University of Texas Health Science Center at Houston)
+ -3 AuthorsXiaobo Zhou40
Estimated H-index: 40
(University of Texas Health Science Center at Houston)
Abstract Long noncoding RNAs (lncRNAs) have been shown to play an important role in tumor biogenesis and prognosis. The glioma is a grade classified cancer, however, we still lack the knowledge on their function during glioma progression. While previous studies have shown how lncRNAs regulate protein-coding gene epigenetically, it is still unclear how lncRNAs are regulated epigenetically. In this study, we firstly analyzed the RNA-seq data systematically across grades II, IV, and IV of glioma sa...
Published in Gene2.64
Deqiang Wang3
Estimated H-index: 3
(Nanjing Medical University),
Xiaoqin Li3
Estimated H-index: 3
(Jiangsu University)
+ -3 AuthorsYongqian Shu39
Estimated H-index: 39
(Nanjing Medical University)
Abstract Background Outcome in adjuvant chemotherapy of gastric cancer (GC) has considerable stage-independent variability, which underscores the need for prognostic or predictive molecular markers. CHAF1A promotes tumor growth while its impact on chemotherapy outcome remains unknown. Methods CHAF1A protein expression was measured in independent discovery and validation sets that included 86 and 325 patients respectively who received fluoropyrimidines-based adjuvant chemotherapy after radical ga...
Published in Gene2.64
Kuralay K. Atageldiyeva (NU: Nazarbayev University), Rita Nemr8
Estimated H-index: 8
+ -3 AuthorsWassim Y. Almawi32
Estimated H-index: 32
(NU: Nazarbayev University)
Abstract Background An association between Apolipoprotein E (Apo E) alleles and genotypes and diabetic nephropathy (DN) was suggested, but with inconsistent results. We tested the relationship between serum lipids, Apo E alleles and genotypes with type 2 diabetes (T2DM), and DN pathogenesis. Methods Study subjects comprised 1389 normoglycemic controls, and 1422 T2DM patients, of whom 825 were normoalbuminuric (DWN), and 597 presented with nephropathy (DN). Results Significantly lower Apo e2, and...
Published in Gene2.64
Gustavo Nunes de Oliveira Costa4
Estimated H-index: 4
(Universidade Salvador),
Camila Alexandrina Figueiredo14
Estimated H-index: 14
(UFBA: Federal University of Bahia)
+ -3 AuthorsMauricio Lima Barreto55
Estimated H-index: 55
Abstract Background Asthma is a complex disease with worldwide public health relevance, is related to environmental causes and a genetic predisposition. The chromosomal 17q12-21 locus has been consistently demonstrated to be associated with asthma risk. The effects of variants in the 17q12-21 locus on childhood asthma were first identified in a genome wide- association study. Since that time, those findings have been replicated in different populations but not in South American populations. Obje...
Published in Gene2.64
Surbhi Verma5
Estimated H-index: 5
(UMKC: University of Missouri–Kansas City),
Viplendra P. S. Shakya6
Estimated H-index: 6
(UMKC: University of Missouri–Kansas City),
Alexander Idnurm33
Estimated H-index: 33
(UMKC: University of Missouri–Kansas City)
Abstract Genes involved in the repair of DNA damage are emerging as playing important roles during the disease processes caused by pathogenic fungi. However, there are potentially hundreds of genes involved in DNA repair in a fungus and some of those genes can play additional roles within the cell. One such gene is RAD23, required for virulence of the human pathogenic fungus Cryptococcus neoformans, that encodes a protein involved in the nucleotide excision repair (NER) pathway. However, Rad23 i...
Published in Gene2.64
Lingyan Yuan , Zhitong Bing (Lanzhou University)+ -3 AuthorsKehu Yang20
Estimated H-index: 20
Abstract Background Existing meta-analysis have shown that the miR-200 family can be taken as a prognostic biomarker for many tumors. However, great heterogeneity was shown in predicting overall survival (OS) and progression-free survival (PFS). Emerging studies indicate that the expression levels of members of the miR-200 family are tissue-specific among various tumor tissues, which may be the main reason of the heterogeneity in predicting survival prognosis of tumor patients with the miR-200 f...
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