Maternal circulating leptin profile during pregnancy and gestational diabetes mellitus

Aims To evaluate the difference in maternal circulating leptin profile between pregnant women with and without gestational diabetes mellitus (GDM). Methods This is a nested case-control study embedded in the Born in Guangzhou Cohort Study in Guangzhou Women and Children’s Medical Center, with 198 GDM cases and 192 controls included. Maternal plasma leptin profile was defined as leptin concentrations measured at early (baseline) and late...