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Diabetes Research and Clinical Practice
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#1Gad Rennert (Technion – Israel Institute of Technology)H-Index: 54
#2Hedy S. Rennert (Technion – Israel Institute of Technology)H-Index: 27
Last. Stephen B. GruberH-Index: 64
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Abstract Background Diabetes has been associated with increased risk of cancer, including breast cancer and colorectal cancer. Metformin, an oral hypoglycemic drug, but not other anti-diabetic drugs, has been associated with reduced risk of breast and of colon cancers in some, but not in other, studies. Methods Data from two large-scale, population-based, case-control studies of breast and colorectal cancers etiology, conducted in Northern Israel since 1998 were analyzed to evaluate the associat...
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#1Dan Guo (Nanjing Medical University)
#2Rong Ju (Nanjing Medical University)
Last. Jiazhen Dai (Nanjing Medical University)
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AIMS Researches on the relationship between maternal pregestational or gestational diabetes and attention deficit/hyperactivity disorder (ADHD) in offspring provided inconsistent findings; therefore, we performed an updated and comprehensive literature review and meta-analysis to evaluate the available evidence. METHOLDS Relevant articles in Pubmed, Web of Science, Cochrane, Embase, and Wanfang database published until January 2019 were searched without language restriction. We performed a meta-...
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Aim To describe the clinical characteristics and outcomes of hospitalized COVID-19 patients with diabetes Methods A retrospective cross-sectional study was conducted among patients admitted to the William Harvey Hospital in England between March 10th and May10th, 2020 with a laboratory-confirmed severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), known as COVID-19 Variation in characteristics, length of stay in hospital, diabetes status, duration of diabetes, control of diabetes, comor...
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Despite a large population and limited health infrastructure, the incidence and mortality of Coronavirus Disease 2019 (COVID-19) has been lower in South Asia than many regions. The underlying reasons and mechanisms for this relative protection are not established. However both genetic and environmental factors might play a role. Polymorphisms in ACE2 gene, ACE gene and in genes for some of the host cell proteases could affect the viral entry and replication. There is some evidence that HLA polym...
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Abstract Aims Rising prevalence of non-communicable diseases world-wide has made diabetes an important comorbidity in patients with coronavirus disease-19 (COVID-19). We sought to review the risk, severity and mortality in COVID-19 and its relation to glycemic control and role of anti-diabetic agents in patients with diabetes. Methods A Boolean search was made in PubMed, MedRxiv and Google Scholar database until May 10, 2020 and full articles with supplementary appendix were retrieved using the ...
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#1Wolfgang Rathmann (HHU: University of Düsseldorf)H-Index: 62
#2Bernard Charbonnel (University of Nantes)H-Index: 29
Last. Iichiro Shimomura (Osaka University)H-Index: 74
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Abstract Aims Using data from DISCOVER (NCT02322762; NCT02226822), a 3-year, global, observational study programme of patients with type 2 diabetes initiating second-line glucose-lowering therapy, we assessed socioeconomic factors associated with hypoglycaemic events and fear of hypoglycaemia. Methods Data were collected at baseline (second-line therapy initiation) and 6, 12 and 24 months. Factors associated with experiencing a hypoglycaemic event at baseline or during follow-up were determined ...
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#1Przemysław Kapusta (Jagiellonian University Medical College)H-Index: 5
#2Paweł Konieczny (Jagiellonian University Medical College)H-Index: 2
Last. Maciej T. Malecki (Jagiellonian University Medical College)H-Index: 33
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Abstract Aims Negative pressure wound therapy (NPWT) is commonly used in diabetic foot ulceration (DFU). The molecular mechanisms of NPWT action, particularly outside of the wound site, have not been described. We assessed NPWT’s effect on circulating miRNA expression levels in type 2 diabetes (T2DM) patients with DFU. Methods We examined 34 T2DM patients treated with either NPWT (n=24) or standard therapy (ST, n=10). The group assignment was based on clinical criteria and local practice. Next-g...
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Abstract Cardiovascular disease is a major cause of death and disability worldwide. Recently, increasing evidence has demonstrated that various lncRNAs play critical roles in the pathogenesis of cardiovascular diseases, including myocardial ischemia and reperfusion (I/R) injury. LncRNAs are transcripts longer than 200 nucleotides. They are considered a class of dynamic noncoding RNAs known to be involved in physiological and pathological conditions with regulatory and structural roles in numerou...
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Top fields of study
Endocrinology
Type 2 diabetes
Insulin
Diabetes mellitus
Medicine