Characterization of RNA‐binding motif 3 (RBM3) protein levels and nuclear architecture changes in aggressive and recurrent prostate cancer

Background The RNA‐binding motif protein 3 (RBM3) has been shown to be upregulated in several types of cancer, including prostate cancer (PCa), compared with normal tissues. Increased RBM3 nuclear expression has been linked to improved clinical outcomes. Aims Given that RBM3 has been hypothesized to play a role in critical nuclear functions such as chromatin remodeling, DNA damage response, and other posttranscriptional processes, we sought to...