Serum insulin levels are associated with vulnerable plaque components in the carotid artery: the Rotterdam Study

To investigate the association between fasting serum insulin and glucose levels with atherosclerotic plaque composition in the carotid artery. Impaired insulin and glucose levels are implicated in the etiology of cardiovascular disease; however, their influence on the formation and composition of atherosclerotic plaque remains unclear.In 1740 participants (mean age 72.9 years, 46% women, 14.4% diabetes mellitus) from the population-based...