Original paper
CTRP1 prevents sepsis-induced cardiomyopathy via Sirt1-dependent pathways
Abstract
C1q/tumor necrosis factor-related protein 1 (CTRP1) has recently been identified as a key regulator of cardio-metabolic diseases. It has been reported that CTRP1 could inhibit the hypertrophic response in mice. However, the effect of CTRP1 on sepsis-induced cardiomyopathy remains completely unknown. Cardiomyocyte-specific CTRP1 overexpression was achieved using an adeno associated virus system in mice. CTRP1 deficiency mice were also subjected...
Paper Details
Title
CTRP1 prevents sepsis-induced cardiomyopathy via Sirt1-dependent pathways
Published Date
May 1, 2020
Volume
152
Pages
810 - 820
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Notes
History