Original paper

Heparin-Binding Copolymer as a Complete Antidote for Low-Molecular-Weight Heparins in Rats

Volume: 373, Issue: 1, Pages: 51 - 61
Published: Jan 14, 2020
Abstract
Bleeding resulting from the application of low-molecular-weight heparins (LMWHs) may be treated with protamine sulfate, but this treatment lacks efficiency; its action against antifactor Xa activity is limited to ∼60%. Moreover, protamine sulfate can cause life-threatening hypersensitivity reactions. We developed diblock heparin-binding copolymer (HBC), which can neutralize the anticoagulant activity of parenteral anticoagulants. In the present...
Paper Details
Title
Heparin-Binding Copolymer as a Complete Antidote for Low-Molecular-Weight Heparins in Rats
Published Date
Jan 14, 2020
Volume
373
Issue
1
Pages
51 - 61
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.