Original paper
Hap2–Ino80-facilitated transcription promotes de novo establishment of CENP-A chromatin
Abstract
Centromeres are maintained epigenetically by the presence of CENP-A, an evolutionarily conserved histone H3 variant, which directs kinetochore assembly and hence centromere function. To identify factors that promote assembly of CENP-A chromatin, we affinity-selected solubilized fission yeast CENP-ACnp1 chromatin. All subunits of the Ino80 complex were enriched, including the auxiliary subunit Hap2. Chromatin association of Hap2 is...
Paper Details
Title
Hap2–Ino80-facilitated transcription promotes de novo establishment of CENP-A chromatin
Published Date
Jan 9, 2020
Journal
Volume
34
Issue
3-4
Pages
226 - 238
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Notes
History