Stable reduction of STARD4 alters cholesterol regulation and lipid homeostasis
Volume: 1865, Issue: 4, Pages: 158609 - 158609
Published: Apr 1, 2020
Abstract
STARD4, a member of the evolutionarily conserved START gene family, is a soluble sterol transport protein implicated in cholesterol sensing and maintenance of cellular homeostasis. STARD4 is widely expressed and has been shown to transfer sterol between liposomes as well as organelles in cells. However, STARD4 knockout mice lack an obvious phenotype, so the overall role of STARD4 is unclear. To model long term depletion of STARD4 in cells, we...
Paper Details
Title
Stable reduction of STARD4 alters cholesterol regulation and lipid homeostasis
DOI
Published Date
Apr 1, 2020
Journal
Volume
1865
Issue
4
Pages
158609 - 158609
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