A Mendelian randomization analysis of circulating lipid traits and breast cancer risk

Conventional epidemiologic studies have evaluated associations between circulating lipid levels and breast cancer risk, but results have been inconsistent. As Mendelian randomization analyses may provide evidence for causal inference, we sought to evaluate potentially unbiased associations between breast cancer risk and four genetically predicted lipid traits.Previous genome-wide association studies (GWAS) have identified 164 discrete variants...