Original paper
Assessment of a Split Homing Based Gene Drive for Efficient Knockout of Multiple Genes
Abstract
Homing based gene drives (HGD) possess the potential to spread linked cargo genes into natural populations and are poised to revolutionize population control of animals. Given that host encoded genes have been identified that are important for pathogen transmission, targeting these genes using guide RNAs as cargo genes linked to drives may provide a robust method to prevent disease transmission. However, effectiveness of the inclusion of...
Paper Details
Title
Assessment of a Split Homing Based Gene Drive for Efficient Knockout of Multiple Genes
Published Date
Feb 1, 2020
Journal
Volume
10
Issue
2
Pages
827 - 837
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Notes
History