Original paper

In-Line Purification: A Key Component to Facilitate Drug Synthesis and Process Development in Medicinal Chemistry

Volume: 11, Issue: 1, Pages: 9 - 15
Published: Dec 12, 2019
Abstract
In-line purification is an important tool for flow chemistry. It enables effective handling of unstable intermediates and integration of multiple synthetic steps. The integrated flow synthesis is useful for drug synthesis and process development in medicinal chemistry. In this article, we overview current states of in-line purification methods. In particular, we focus on four common methods: scavenger column, distillation, nanofiltration, and...
Paper Details
Title
In-Line Purification: A Key Component to Facilitate Drug Synthesis and Process Development in Medicinal Chemistry
Published Date
Dec 12, 2019
Volume
11
Issue
1
Pages
9 - 15
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