The Effect of the Urinary and Fecal Microbiota on Lower Urinary Tract Symptoms Measured by the International Prostate Symptom Score: Analysis Utilizing Next-Generation Sequencing

To examine the correlation between urinary and faecal microbial profiles and the different aspects of lower urinary tract symptoms (LUTS) in men, as there is accumulating evidence that variations in the human microbiota may promote different benign disease conditions.We extracted total DNA from urine and faecal samples of a group of men, under an Institutional Review Board-approved protocol. At the same time, International Prostate Symptom Score...