Transglutaminase 2 limits the extravasation and the resultant myocardial fibrosis associated with factor XIII-A deficiency
Abstract
Background and aimsTransglutaminase (TG) 2 and Factor (F) XIII-A have both been implicated in cardiovascular protection and repair. This study was designed to differentiate between two competing hypotheses: that TG2 and FXIII-A mediate these functions in mice by fulfilling separate roles, or that they act redundantly in this respect.MethodsAtherosclerosis was assessed in brachiocephalic artery plaques of fat-fed mixed strain apolipoprotein...
Paper Details
Title
Transglutaminase 2 limits the extravasation and the resultant myocardial fibrosis associated with factor XIII-A deficiency
Published Date
Feb 1, 2020
Journal
Volume
294
Pages
1 - 9
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