doi.org/10.1016/j.oraloncology.2019.104516
Original paper

Validation and characterisation of prognostically significant PD-L1+ immune cells in HPV+ oropharyngeal squamous cell carcinoma

..., Benjamin Solomon
66
Oral Oncology4.00
Volume: 101, Pages: 104516 - 104516
Published: Feb 1, 2020
Abstract
We previously showed in human papillomavirus positive oropharyngeal squamous cell carcinoma (HPV+OPSCC) that the presence of intratumoral (IT) PD-L1+ immune cells (ICs) or CD8+ infiltrating ICs are of prognostic value. Here we report the prognostic significance of these immune biomarkers in an independent validation cohort of 177 HPV+OPSCC patients. IT and stromal (S) localisation of PD-L1+ and CD8+ ICs were scored. High abundance (≥5%) of...
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Paper Details
Title
Validation and characterisation of prognostically significant PD-L1+ immune cells in HPV+ oropharyngeal squamous cell carcinoma
DOI
doi.org/10.1016/j.oraloncology.2019.104516
Published Date
Feb 1, 2020
Journal
Oral Oncology
Volume
101
Pages
104516 - 104516
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