DNA methylation biomarkers discovered in silico detect cancer in liquid biopsies from non-small cell lung cancer patients
Abstract
Identification of cancer-specific methylation of DNA released by tumours can be used for non-invasive diagnostics and monitoring. We previously reported in silico identification of DNA methylation loci specifically hypermethylated in common human cancers that could be used as epigenetic biomarkers. Using DNA methylation specific qPCR we now clinically tested a group of these cancer-specific loci on cell-free DNA (cfDNA) extracted from the plasma...
Paper Details
Title
DNA methylation biomarkers discovered in silico detect cancer in liquid biopsies from non-small cell lung cancer patients
Published Date
Nov 27, 2019
Journal
Volume
15
Issue
4
Pages
419 - 430
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