Surface modification of Ti6Al4V by forming hybrid self-assembled monolayers and its effect on collagen-I adsorption, osteoblast adhesion and integrin expression

Silanization is a widely explored chemical technique to modify surfaces for tailoring physio-chemical properties like surface chemistry and wettability but its impact on bio-interfaces interaction i.e. protein adsorption and cellular responses is not well understood. This work focusses on modulating surface properties of Ti6Al4V to study their behavior towards collagen-I (Col-I) adsorption and subsequently on osteoblast adhesion and integrin...