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Abshar Hasan
Indian Institute of Technology Guwahati
Surface modificationSelf-assembled monolayerOrganic chemistryMaterials scienceProtein adsorption
17Publications
9H-index
202Citations
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Publications 23
Newest
#1R.R. Behera (KIIT: KIIT University)
#2Apurba Das (IITG: Indian Institute of Technology Guwahati)H-Index: 2
Last. M.R. Sankar (IITs: Indian Institutes of Technology)
view all 6 authors...
Abstract The present investigation focuses on the deposition of biphasic calcium phosphate (BCP) and titania (TiO2) composite films on Ti-6Al-4V substrates using radio frequency (RF) magnetron sputtering. Three different compositions such as 100% BCP, 25% TiO2-75% BCP and 50% TiO2-50% BCP films were fabricated, and the physical, mechanical and biological behaviors of the films were analyzed. Post deposition, the films were annealed at 700 °C for 2 h to induce the crystallinity and to study its e...
Source
#1Abshar Hasan (University of Strathclyde)H-Index: 9
#2Kyueui Lee (University of California, Berkeley)H-Index: 6
Last. King Hang Aaron Lau (University of Strathclyde)H-Index: 19
view all 8 authors...
Microbial surface attachment negatively impacts a wide range of devices from water purification membranes to biomedical implants. Mimics of antimicrobial peptides (AMPs) constituted from poly(N‐substituted glycine) “peptoids” are of great interest as they resist proteolysis and can inhibit a wide spectrum of microbes. We investigate how terminal modification of a peptoid AMP‐mimic and its surface immobilization affect antimicrobial activity. We also demonstrate a convenient surface modification ...
Source
#1Valeria Castelletto (University of Reading)H-Index: 39
#2Jani Seitsonen (Aalto University)H-Index: 17
Last. King Hang Aaron Lau (University of Strathclyde)H-Index: 19
view all 9 authors...
Peptoids are biofunctional N-substituted glycine peptidomimics. Their self-assembly is of fundamental interest because they demonstrate alternatives to conventional peptide structures based on back...
Source
#1Abshar Hasan (IITG: Indian Institute of Technology Guwahati)H-Index: 9
#2Lalit M. Pandey (IITG: Indian Institute of Technology Guwahati)H-Index: 13
Abstract Silanization is a widely explored chemical technique to modify surfaces for tailoring physio-chemical properties like surface chemistry and wettability but its impact on bio-interfaces interaction i.e. protein adsorption and cellular responses is not well understood. This work focusses on modulating surface properties of Ti6Al4V to study their behavior towards collagen-I (Col-I) adsorption and subsequently on osteoblast adhesion and integrin expression. The moderate hydrophobic Ti6Al4V ...
Source
#1Valeria Castelletto (University of Reading)H-Index: 39
#2Ann M. Chippindale (University of Reading)H-Index: 26
Last. King Hang Aaron Lau (University of Strathclyde)H-Index: 19
view all 6 authors...
An aromatic peptoid analogue of the diphenylalanine dipeptide self-assembles in aqueous solution and the first crystal structure was obtained for this class of compound. This reveals molecular packing stabilized by networks of hydrogen bonds. Free-floating nanosheet lamellar structures are observed in solution, which form via cooperative intermolecular interactions driven by π stacking.
1 CitationsSource
#1Sunayan Deka (IITG: Indian Institute of Technology Guwahati)H-Index: 1
#2Varun Saxena (IITG: Indian Institute of Technology Guwahati)H-Index: 7
Last. Lalit M. Pandey (IITG: Indian Institute of Technology Guwahati)H-Index: 13
view all 5 authors...
Abstract The use of gadolinium orthoferrite for biomedical application like as contrast agents for magnetic resonance imaging (MRI) has been found to be very promising due to its fascinating properties. The present study focuses on the determination of the effect of the gadolinium concentration in the formation biphasic α-Fe2O3-GdFeO3 for hyperthermia applications. An in-situ sol-gel technique was adopted for the synthesis of biphasic orthoferrites with four different gadolinium concentrations. ...
8 CitationsSource
#1Rasmi Ranjan Behera (IITG: Indian Institute of Technology Guwahati)H-Index: 3
#2Abshar Hasan (IITG: Indian Institute of Technology Guwahati)H-Index: 9
Last. Lalit M. Pandey (IITG: Indian Institute of Technology Guwahati)H-Index: 13
view all 4 authors...
Abstract In the present study, the morphology and composition of Titanium alloy (Ti–6Al–4 V) surfaces were modified by laser cladding (LC) process to enhance the biocompatibility and bioactivity of orthopaedic implants. Ti–6Al–4 V substrates were processed using a pulsed Nd:YAG laser with various precursors: 100% HA and functionally graded TiO 2 -HA material (FGM). A set of laser parameters having 21.6 J/mm 2 laser energy density or irradiance was applied for cladding, to execute a comparative s...
2 CitationsSource
#1Abshar Hasan (IITG: Indian Institute of Technology Guwahati)H-Index: 9
#2Sudip K. Pattanayek (IITD: Indian Institute of Technology Delhi)H-Index: 11
Last. Lalit M. Pandey (IITG: Indian Institute of Technology Guwahati)H-Index: 13
view all 3 authors...
Surface modification plays a vital role in regulating protein adsorption and subsequently cell adhesion. In the present work, we prepared nanoscaled modified surfaces using silanization and characterized them using Fourier-transform infrared spectroscopy (FTIR), water contact angle (WCA), and atomic force microscopy (AFM). Five different (amine, octyl, mixed, hybrid, and COOH) surfaces were prepared based on their functionality and varying wettability and their effect on protein adsorption and i...
4 CitationsSource
#1Abshar Hasan (IITG: Indian Institute of Technology Guwahati)H-Index: 9
#2Gyan Waibhaw (IITG: Indian Institute of Technology Guwahati)H-Index: 3
Last. Lalit M. Pandey (IITG: Indian Institute of Technology Guwahati)H-Index: 13
view all 3 authors...
Physicochemical interactions of proteins with surfaces mediate the interactions between the implant and the biological system. Surface chemistry of the implant is crucial as it regulates the events at the interface. The objective of this study was to explore the performance of modified surfaces for such interactions relevant to various biomedical applications. Because of a wide range of surface wettability, we aimed to study protein behavior (i.e., conformational changes and their packing) durin...
12 CitationsSource
#1Ajeet Singh (IITG: Indian Institute of Technology Guwahati)H-Index: 3
#2Abshar Hasan (IITG: Indian Institute of Technology Guwahati)H-Index: 9
Last. Lalit M. Pandey (IITG: Indian Institute of Technology Guwahati)H-Index: 13
view all 4 authors...
5 CitationsSource
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